Article
Polymorphisms and haplotypes in the YWHAE gene increase susceptibility to bipolar disorder in Chinese Han population.
The Journal of clinical psychiatry - 1 Oct 2012
Liu Jie, Li Zhi-Qiang, Li Jun-Yan, Li Tao, Wang Ti, Li You, Xu Yi-Feng, Feng Guo-Yin, Shi Yong-Yong, He Lin
Abstract excerpt
BACKGROUND: Schizophrenia and bipolar disorder are 2 major psychiatric illnesses sharing some specific genetic risk factors. Increasing evidence suggests the 2 illnesses might be more closely related than previously considered. OBJECTIVE: To test this hypothesis, we investigated the allele and genotype frequencies of 11 single nucleotide polymorphisms (SNPs) and the haplotypes in these SNPs of the YWHAE gene....
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