Correlation of length of VNTR alleles at the X-linked MAOA gene and phenotypic effect in Tourette syndrome and drug abuse.

doi:10.1038/sj.mp.4000326

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Article

Correlation of length of VNTR alleles at the X-linked MAOA gene and phenotypic effect in Tourette syndrome and drug abuse.

Molecular psychiatry - 1 Jan 1998

Gade R, Muhleman D, Blake H, MacMurray J, Johnson P, Verde R, Saucier G, Comings D E

Abstract excerpt

Abnormalities in monoamine oxidase (MAO) levels have been implicated in a wide range of psychiatric disorders. We have examined a VNTR polymorphism at the X-linked MAOA gene to test two hypotheses: (1) Do variants of the MAOA gene play a role in any of the behavioral disorders associated with Tou...

Topics

Alleles
Analysis of Variance
Chromosome Mapping
Family
Humans
Isoenzymes
Linkage Disequilibrium
Mental Disorders
Minisatellite Repeats
Monoamine Oxidase
Multivariate Analysis
Phenotype
Quantitative Trait, Heritable
Reference Values
Regression Analysis

Source

Open in PubMed

Identifiers

PMID: 9491813
DOI: 10.1038/sj.mp.4000326

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9491813-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Substance-Related Disorders

Tourette Syndrome

X Chromosome