Article
Analysis of monoamine oxidase A (MAO-A) promoter polymorphism in male heroin-dependent subjects: behavioural and personality correlates.
Journal of neural transmission (Vienna, Austria : 1996) - 1 May 2004
Gerra G, Garofano L, Bosari S, Pellegrini C, Zaimovic A, Moi G, Bussandri M, Moi A, Brambilla F, Mameli A, Pizzamiglio M, Donnini C
Abstract excerpt
The promoter of the monoamine oxidase A (MAO-A) gene was analysed to test whether length variation of the repeat polymorphism contributes to variation in individual vulnerability to aggressive-criminal behaviour, and liability to heroin dependence. The repeat number of the MAO-A polymorphism was assessed in 199 male subjects of Italian descent, a sample comprising 95 healthy subjects and 104 heroin-dependent...
Topics
- Adult
- Aggression
- Antisocial Personality Disorder
- Dangerous Behavior
- Gene Frequency
- Genetic Predisposition to Disease
- Heroin Dependence
- Humans
- Male
- Middle Aged
- Monoamine Oxidase
- Polymerase Chain Reaction
- Polymorphism, Genetic