Article
Preliminary evidence for an association of a dinucleotide repeat polymorphism at the MAOA gene with early onset alcoholism/substance abuse.
American journal of medical genetics - 24 Apr 1995
Vanyukov M M, Moss H B, Yu L M, Tarter R E, Deka R
Abstract excerpt
An association between the liability to early onset alcoholism/substance abuse and a recently discovered dinucleotide repeat length polymorphism at the MAOA gene (MAOCA-1) was examined using polymerase chain reaction (PCR). A significant correlation between the presence/absence of the disorder and the length of the MAOCA-1 repeat was found in males, but not females, with "long" alleles (repeat length above 115...
Topics
- Adolescent
- Age of Onset
- Alcoholism
- Alleles
- Base Sequence
- Case-Control Studies
- DNA Primers
- Dinucleotide Repeats
- Female
- Gene Frequency
- Humans