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Article

Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism.

Psychiatry research - 19 Apr 1999

Samochowiec J, Lesch K P, Rottmann M, Smolka M, Syagailo Y V, Okladnova O, Rommelspacher H, Winterer G, Schmidt L G, Sander T

Abstract excerpt

We analyzed a novel functional 30-bp repeat polymorphism in the promoter region of the X-chromosomal monoamine oxidase A gene (MAOA) to test whether length variation of the repeat polymorphism contributes to variation in the individual vulnerability to antisocial behavior and liability to alcohol dependence. The repeat number (3-5) of the MAOA polymorphism was assessed in 488 male subjects of German descent, a...

Topics

Adult
Alcoholism
Alleles
Antisocial Personality Disorder
Gene Expression
Genotype
Humans
Male
Monoamine Oxidase
Polymorphism, Genetic
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

X Chromosome

Source

Identifiers

PMID: 10359483
DOI: 10.1016/s0165-1781(99)00020-7

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism.PMID 10359483Read ↗

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