Article
Association analysis of the dopamine D4 gene exon III VNTR and heroin abuse in Chinese subjects.
Molecular psychiatry - 1 Sept 1997
Li T, Xu K, Deng H, Cai G, Liu J, Liu X, Wang R, Xiang X, Zhao J, Murray R M, Sham P C, Collier D A
Abstract excerpt
Although social and cultural influences are clearly important, family, twin and adoption studies indicate that genes contribute significantly to substance abuse. Substance abuse is associated with novelty seeking, a heritable human personality trait which may be influenced by alleles of the dopamine D4 (DRD4) gene exon III VNTR. Consequently Kotler et al analysed the DRD4 VNTR in opiate-dependent subjects from...
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