Article
Use of echocardiography for the phenotypic assessment of genetically altered mice.
Physiological genomics - 13 May 2003
Collins Keith A, Korcarz Claudia E, Lang Roberto M
Abstract excerpt
Transgenic mice displaying abnormalities in cardiac development and function represent a powerful new tool for understanding molecular mechanisms underlying normal cardiovascular function and the pathophysiological bases of human cardiovascular disease. Complete cardiac evaluation of phenotypic changes in mice requires the ability to noninvasively assess cardiovascular structure and function in a serial manner....
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