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Article

RNA-binding protein TIAR is essential for primordial germ cell development

3 Mar 1998

Abstract excerpt

Primordial germ cells (PGCs) give rise to both eggs and sperm via complex maturational processes that require both cell migration and proliferation. However, little is known about the genes controlling gamete formation during the early stages of PGC development. Although several mutations are known to severely reduce the number of PGCs reaching and populating the genital ridges, the molecular identity of only two...

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PMID: 9482885
DOI: 10.1073/pnas.95.5.2331

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