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Article

Disruption of genital ridge development causes aberrant primordial germ cell proliferation but does not affect their directional migration.

BMC biology - 5 Mar 2013

Chen Su-Ren, Zheng Qiao-Song, Zhang Yang, Gao Fei, Liu Yi-Xun

Abstract excerpt

BACKGROUND: The directional migration and the following development of primordial germ cells (PGCs) during gonad formation are key steps for germline development. It has been proposed that the interaction between germ cells and genital ridge (GR) somatic cells plays essential roles in this process. However, the in vivo functional requirements of GR somatic cells in germ cell development are largely unknown....

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Identifiers

PMID: 23497137
DOI: 10.1186/1741-7007-11-22
PMCID: PMC3652777

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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