Apolipoprotein E gene in Parkinson's disease, Lewy body dementia and Alzheimer's disease.

Abstract excerpt

Apolipoprotein E (Apo E) epsilon 4 allele is a risk factor for early and late onset Alzheimer's disease. This prompted us to examine other neurophyschiatric phenotypes. Epsilon 4 allele was significantly enriched in Lewy body dementia (n = 39) but not in Parkinson's disease (n = 50) or Schizophre...

Topics

• Aged
• Alleles
• Alzheimer Disease
• Apolipoproteins E
• Dementia
• Female
• Humans
• Lewy Bodies
• Male
• Membrane Proteins
• Middle Aged
• Parkinson Disease
• Presenilin-1
• Risk Factors
• Schizophrenia