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Article

Lymph node human immunodeficiency virus RNA levels and resistance mutations in patients receiving high-dose saquinavir.

The Journal of infectious diseases - 1 Feb 1998

Schapiro J M, Winters M A, Vierra M, Crawford S, Merigan T C

Abstract excerpt

The development of resistance mutations and human immunodeficiency virus (HIV) RNA levels were compared in lymph nodes and plasma of patients receiving antiretroviral therapy. Ten HIV-positive patients receiving high-dose saquinavir monotherapy (3600 or 7200 mg/day) underwent 14 lymph node biopsies before and during therapy. HIV RNA levels and appearance of resistance mutations to saquinavir were determined in...

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Identifiers

PMID: 9466542
DOI: 10.1086/517380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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