Article
A molecular variant of angiotensinogen is associated with diabetic nephropathy in IDDM.
Diabetes - 1 Sept 1996
Fogarty D G, Harron J C, Hughes A E, Nevin N C, Doherty C C, Maxwell A P
Abstract excerpt
Recent studies have suggested that an inherited predisposition to essential hypertension may increase susceptibility to nephropathy for patients with IDDM. Essential hypertension has been linked to the angiotensinogen (AGT) gene in genetic linkage studies in American and European populations. A molecular variant (M235T), which has a functional effect, has been described with highest plasma AGT levels being...
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