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Article

Factor V Q506 mutation (activated protein C resistance) associated with reduced intrapartum blood loss--a possible evolutionary selection mechanism.

Thrombosis and haemostasis - 1 Jan 1998

Lindqvist P G, Svensson P J, Dahlbäck B, Marsál K

Abstract excerpt

OBJECTIVES: To ascertain whether relationship exists between the presence of APC resistance [a hypercoagulable state due to a mutation (R506Q) in the factor V gene] and the occurrence of pre-eclampsia (PE), intrauterine growth retardation (IUGR), and pregnancy bleeding complications. DESIGN: A retrospective study. SUBJECTS: A study group of 122 women with PE and/or IUGR during a recent pregnancy and a control...

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Source

Identifiers

PMID: 9459326

Genes

APC

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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