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Article

Characterization of MgtC, a virulence factor of Salmonella enterica Serovar Typhi.

PloS one - 1 Jan 2009

Retamal Patricio, Castillo-Ruiz Mario, Mora Guido C

Abstract excerpt

The MgtC is a virulence factor in Salmonella Typhimurium that is required for growth at low-Mg2+ concentrations and intramacrophage survival. This gene is codified in a conserved region of the Salmonella pathogenicity island 3 (SPI-3), and is also present in the chromosome of other Salmonella serovars. In this study we characterized the MgtC factor in S. Typhi, a human specific pathogen, by using mgtC and SPI-3...

Topics

Bacterial Proteins
Cation Transport Proteins
Conserved Sequence
Genes, Bacterial
Genes, Reporter
Magnesium
Phenotype
Salmonella typhi
Virulence Factors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19436747
DOI: 10.1371/journal.pone.0005551
PMCID: PMC2677668

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