Article
Molecular inhibition of HIV type 1 by HIV type 2: effectiveness in peripheral blood mononuclear cells.
AIDS research and human retroviruses - 1 Jan 1998
Al-Harthi L, Owais M, Arya S K
Abstract excerpt
HIV-2 downregulates HIV-1 in human primary peripheral blood mononuclear cells (PBMCs). Although the effect of HIV-2 on HIV-1 in human CD4+ T cell lines was previously reported, the present observations with PBMCs are a necessary demonstration before considering animal model and clinical studies....
Topics
- Antibiosis
- HIV-1
- HIV-2
- Humans
- Leukocytes, Mononuclear
- Mutation
- RNA, Viral