Article
Inactivating BK channels in rat chromaffin cells may arise from heteromultimeric assembly of distinct inactivation-competent and noninactivating subunits.
Biophysical journal - 1 Jan 1998
Ding J P, Li Z W, Lingle C J
Abstract excerpt
Inactivating and noninactivating variants of large-conductance, Ca2+-dependent, voltage-dependent BK-type channels are found in rat chromaffin cells and are largely segregated into different cells. Here we test the hypothesis that, within the population of cells that express inactivating BK curre...
Topics
- Animals
- Cell Membrane
- Cells, Cultured
- Charybdotoxin
- Chromaffin Cells
- Cytosol
- Genetic Variation
- Large-Conductance Calcium-Activated Potassium Channels
- Macromolecular Substances
- Membrane Potentials
- Models, Biological
- Models, Chemical
- Patch-Clamp Techniques
- Phenotype
- Potassium Channels
- Potassium Channels, Calcium-Activated
- Rats
- Time Factors