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Article

Direct observation of a preinactivated, open state in BK channels with beta2 subunits.

The Journal of general physiology - 1 Feb 2006

Benzinger G Richard, Xia Xiao-Ming, Lingle Christopher J

Abstract excerpt

Proteins arising from the Slo family assemble into homotetramers to form functional large-conductance, Ca2+- and voltage-activated K+ channels, or BK channels. These channels are also found in association with accessory beta subunits, which modulate several aspects of channel gating and expression. Coexpression with either of two such subunits, beta2 or beta3b, confers time-dependent inactivation onto BK...

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Source

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Identifiers

PMID: 16418401
DOI: 10.1085/jgp.200509425
PMCID: PMC2151486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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