Article
APC genotype, polyp number, and surgical options in familial adenomatous polyposis.
Annals of surgery - 1 Jan 1998
Wu J S, Paul P, McGannon E A, Church J M
Abstract excerpt
OBJECTIVE: This study was performed to examine the relation between phenotypic expression in patients with familial adenomatous polyposis (FAP) and the site of mutations in the APC (adenomatous polyposis coli) gene. The ability of APC mutations to predict surgical outcome was also investigated. S...
Topics
- Adenomatous Polyposis Coli
- Adolescent
- Adult
- Child
- Colectomy
- DNA Mutational Analysis
- Genes, APC
- Genotype
- Germ-Line Mutation
- Humans
- Patient Selection
- Polymorphism, Single-Stranded Conformational
- Predictive Value of Tests
- Prognosis
- Retrospective Studies
- Sequence Analysis, DNA
- Severity of Illness Index
- Treatment Outcome