Article
APC genotype, polyp number, and surgical options in familial adenomatous polyposis.
Annals of surgery - 1 Jan 1998
Wu J S, Paul P, McGannon E A, Church J M
Abstract excerpt
OBJECTIVE: This study was performed to examine the relation between phenotypic expression in patients with familial adenomatous polyposis (FAP) and the site of mutations in the APC (adenomatous polyposis coli) gene. The ability of APC mutations to predict surgical outcome was also investigated. SUMMARY BACKGROUND DATA: Germline mutations in the APC gene cause FAP and can now be identified by direct mutational...
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