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Article

Activation of antiviral protein kinase leads to immunoglobulin E class switching in human B cells.

Journal of virology - 1 Feb 1998

Rager K J, Langland J O, Jacobs B L, Proud D, Marsh D G, Imani F

Abstract excerpt

An epidemiologic association between viral infections and the onset of asthma and allergy has been documented. Also, evidence from animal and human studies has suggested an increase in antigen-specific immunoglobulin E (IgE) production during viral infections, and elevated levels of IgE are characteristic of human asthma and allergy. Here, we provide molecular evidence for the roles of viral infection and of...

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Share to B-Lymphocytes
Share to eIF-2 Kinase
Share to Gene Expression Regulation, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Class Switching

Share to Immunoglobulin E

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Share to Tumor Cells, Cultured

Share to Vaccinia virus

Source

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Identifiers

PMID: 9445015
DOI: 10.1128/JVI.72.2.1171-1176.1998
PMCID: PMC124593

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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