Differential requirements for conserved E2 binding sites in the life cycle of oncogenic human papillomavirus type 31.

Abstract excerpt

Human papillomavirus (HPV) E2 proteins regulate viral replication by binding to sites in the upstream regulatory region (URR) and by complex formation with the E1 origin recognition protein. In the genital HPV types, the distribution and location of four E2 binding sites (BS1 to BS4) which flank a single E1 binding site are highly conserved. We have examined the roles of these four E2 sites in the viral life...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Binding Sites
• Share to Conserved Sequence
• Share to Genome, Viral