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Article

Transactivation by the E2 protein of oncogenic human papillomavirus type 31 is not essential for early and late viral functions.

Journal of virology - 1 Oct 1998

Stubenrauch F, Colbert A M, Laimins L A

Abstract excerpt

The activation of transcription and of DNA replication are, in some cases, mediated by the same proteins. A prime example is the E2 protein of human papillomaviruses (HPVs), which binds ACCN6GGT sequences and activates heterologous promoters from multimerized binding sites. The E2 protein also has functions in replication, where it complexes with the virally encoded origin recognition protein, E1. Much of the...

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Identifiers

PMID: 9733852
DOI: 10.1128/JVI.72.10.8115-8123.1998
PMCID: PMC110149

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