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Article

Human Sex Hormone-binding Globulin is Expressed in Testicular Germ Cells and not in Sertoli Cells

1 Apr 2006

Abstract excerpt

The human sex hormone-binding globulin ( SHBG) gene contains at least two transcription units. A 4.3 kb human SHBG transcription unit encodes the precursor polypeptide, which is processed and secreted by hepatocytes as plasma SHBG. The proximal promoter of this transcription unit differs from the corresponding sequence in other mammals, in which it is also expressed in Sertoli cells. In particular, its proximal...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Hormonal and reproductive studies
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PMID: 16700003
DOI: 10.1055/s-2006-925336

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