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Molecular and Functional Characterization of Sex Hormone Binding Globulin in Zebrafish

30 Jul 2004

Abstract excerpt

SHBG (sex hormone binding globulin) transports androgens and estrogens in the blood of vertebrates including fish. Orthologs of SHBG in fish are poorly defined, and we have now obtained a zebrafish SHBG cDNA and characterized the zebrafish SHBG gene and protein through molecular biological, biochemical, and informatics approaches. Amino-terminal analysis of zebrafish SHBG indicated that its deduced precursor...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Hormonal and reproductive studies
Share to Reproductive biology and impacts on aquatic species

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PMID: 15284198
DOI: 10.1210/en.2004-0678

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