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Article

Diverse Roles for Sex Hormone-Binding Globulin in Reproduction

25 May 2011

Abstract excerpt

Sex hormone-binding globulin (SHBG) transports androgens and estrogens in blood and regulates their access to target tissues. Hepatic production of SHBG fluctuates throughout the life cycle and is influenced primarily by metabolic and hormonal factors. Genetic differences also contribute to interindividual variations in plasma SHBG levels. In addition to controlling the plasma distribution, metabolic clearance,...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Hormonal and reproductive studies
Share to Reproductive biology and impacts on aquatic species

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PMID: 21613632
DOI: 10.1095/biolreprod.111.092593

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