Article
Molecular divergence of the sia locus in different serogroups of Neisseria meningitidis expressing polysialic acid capsules.
Molecular & general genetics : MGG - 1 Dec 1997
Claus H, Vogel U, Mühlenhoff M, Gerardy-Schahn R, Frosch M
Abstract excerpt
The serogroups B, C, W135 and Y of Neisseria meningitidis express chemically and immunologically distinct capsular polysaccharides containing sialic acid. In the case of serogroup B meningococci sialic acid is synthesized by the gene products of a locus termed sia and forms the homopolymers of th...
Topics
- Biological Evolution
- Cloning, Molecular
- Genes, Bacterial
- Genetic Variation
- Neisseria meningitidis
- Open Reading Frames
- Recombinant Proteins
- Sequence Analysis
- Serotyping
- Sialic Acids
- Sialyltransferases
