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Article

Complement factor C3 deposition and serum resistance in isogenic capsule and lipooligosaccharide sialic acid mutants of serogroup B Neisseria meningitidis.

Infection and immunity - 1 Oct 1997

Vogel U, Weinberger A, Frank R, Müller A, Köhl J, Atkinson J P, Frosch M

Abstract excerpt

Serogroup B meningococci express sialic acids on their surfaces as a modification of the lipooligosaccharide (LOS) and as capsular material consisting of alpha2,8-linked sialic acid homopolymers. The aim of this study was to elucidate the impact of each sialic acid component on the deposition of complement factor C3 and serum resistance. For this purpose, we used isogenic mutants deficient in capsule expression...

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Source

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Identifiers

PMID: 9317002
DOI: 10.1128/iai.65.10.4022-4029.1997
PMCID: PMC175578

Genes

NHS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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