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Article

Identification of a genetic locus essential for capsule sialylation in type III group B streptococci.

Infection and immunity - 1 Feb 1992

Wessels M R, Haft R F, Heggen L M, Rubens C E

Abstract excerpt

The type III capsular polysaccharide of group B streptococci (GBS) consists of a linear backbone with short side chains ending in residues of N-acetylneuraminic acid, or sialic acid. The presence of sialic acid on the surface of the organism inhibits activation of the alternative pathway of complement and is thought to be an important element in the virulence function of the capsule. We showed previously that a...

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Source

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Identifiers

PMID: 1309720
DOI: 10.1128/iai.60.2.392-400.1992
PMCID: PMC257641

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