Article
Structural and kinetic characterizations of the polysialic acid O-acetyltransferase OatWY from Neisseria meningitidis.
The Journal of biological chemistry - 4 Sept 2009
Lee Ho Jun, Rakić Bojana, Gilbert Michel, Wakarchuk Warren W, Withers Stephen G, Strynadka Natalie C J
Abstract excerpt
The neuroinvasive pathogen Neisseria meningitidis has 13 capsular serogroups, but the majority of disease is caused by only 5 of these. Groups B, C, Y, and W-135 all display a polymeric sialic acid-containing capsule that provides a means for the bacteria to evade the immune response during infec...
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