Article
Identification of the essential amino acid residues in lukS for the hemolytic activity of staphylococcal leukocidin towards rabbit erythrocytes.
Bioscience, biotechnology, and biochemistry - 1 Dec 1997
Nariya H, Shimatani A, Tomita T, Kamio Y
Abstract excerpt
Staphylococcus aureus V8 (ATCC 49775) produces Panton-Valentine leukocidin (PVL) and leukocidin (Luk). PVL and Luk consist of LukF-PV and LukS-PV, and LukF and LukS, respectively. LukF and LukS cooperatively and strongly lyse rabbit erythrocytes besides human and rabbit polymorphonuclear leukocyt...
Topics
- Amino Acid Sequence
- Amino Acids, Essential
- Animals
- Bacterial Proteins
- Bacterial Toxins
- Base Sequence
- Chimera
- Erythrocytes
- Escherichia coli
- Exotoxins
- Hemolysis
- Humans
- Leukocidins
- Molecular Sequence Data
- Mutation
- Neutrophils
- Rabbits
- Staphylococcus aureus