Article
Identification of the essential amino acid residues in lukS for the hemolytic activity of staphylococcal leukocidin towards rabbit erythrocytes.
Bioscience, biotechnology, and biochemistry - 1 Dec 1997
Nariya H, Shimatani A, Tomita T, Kamio Y
Abstract excerpt
Staphylococcus aureus V8 (ATCC 49775) produces Panton-Valentine leukocidin (PVL) and leukocidin (Luk). PVL and Luk consist of LukF-PV and LukS-PV, and LukF and LukS, respectively. LukF and LukS cooperatively and strongly lyse rabbit erythrocytes besides human and rabbit polymorphonuclear leukocytes. LukF and LukS-PV also cooperatively lysed rabbit erythrocytes, but its activity was only 4% of that in combination...
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