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Article

An N-terminal region of LukF of staphylococcal leukocidin/gamma-hemolysin crucial for the biological activity of the toxin.

Bioscience, biotechnology, and biochemistry - 1 Jul 1998

Kaneko J, Mascarenas A L, Huda M N, Tomita T, Kamio Y

Abstract excerpt

The two staphylococcal bi-component toxins, leukocidin and gamma-hemolysin share LukF [Kamio et al, FEBS Lett., 321, 15-18 (1993)]. This report identifies the pivotal amino acid residues in the N-terminal region of LukF for the leukocytolytic and hemolytic activities in the presence of LukS and H...

Topics

Amino Acid Sequence
Bacterial Proteins
Bacterial Toxins
Erythrocytes
Escherichia coli
Hemolysin Proteins
Humans
Leukocidins
Molecular Sequence Data
Mutation
Staphylococcus aureus

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Identifiers

PMID: 9720234
DOI: 10.1271/bbb.62.1465

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9720234-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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An N-terminal region of LukF of staphylococcal leukocidin/gamma-hemolysin crucial for the biological activity of the toxin.PMID 9720234Read ↗

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Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH.Semantic proximity Read ↗

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Characterization of a novel structural member, LukE‐LukD, of the bi‐component staphylococcal leucotoxins familySemantic proximity Read ↗

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