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Article

Human T-cell recognition of synthetic peptides representing conserved and variant sequences from the merozoite surface protein 2 of Plasmodium falciparum.

Immunology letters - 1 Jun 1997

Theander T G, Hviid L, Dodoo D, Afari E A, Jensen J B, Rzepczyk C M

Abstract excerpt

Merozoite surface protein 2 (MSP2) is a malaria vaccine candidate currently undergoing clinical trials. We analyzed the peripheral blood mononuclear cell (PBMC) response to synthetic peptides corresponding to conserved and variant regions of the FCQ-27 allelic form of MSP2 in Ghanaian individuals from an area of hyperendemic malaria transmission and in Danes without exposure to malaria. PBMC from 20-39% of...

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PMID: 9436461
DOI: 10.1016/s0165-2478(96)02685-5

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