Article
Human T-cell recognition of synthetic peptides representing conserved and variant sequences from the merozoite surface protein 2 of Plasmodium falciparum.
Immunology letters - 1 Jun 1997
Theander T G, Hviid L, Dodoo D, Afari E A, Jensen J B, Rzepczyk C M
Abstract excerpt
Merozoite surface protein 2 (MSP2) is a malaria vaccine candidate currently undergoing clinical trials. We analyzed the peripheral blood mononuclear cell (PBMC) response to synthetic peptides corresponding to conserved and variant regions of the FCQ-27 allelic form of MSP2 in Ghanaian individuals...
Topics
- Adult
- Amino Acid Sequence
- Animals
- Antigens, Protozoan
- Conserved Sequence
- Denmark
- Genetic Variation
- Ghana
- Humans
- Interferon-gamma
- Interleukin-4
- Lymphocyte Activation
- Malaria Vaccines
- Malaria, Falciparum
- Molecular Sequence Data
- Peptide Fragments
- Plasmodium falciparum
- Protozoan Proteins