Article
Cloning of human T cells specific for measles virus haemagglutinin and nucleocapsid.
Clinical and experimental immunology - 1 Aug 1990
Ilonen J, Mäkelä M J, Ziola B, Salmi A A
Abstract excerpt
T cell lines specific for measles virus (MV) were generated from blood of two DR1/DR2 heterozygous healthy donors with a history of past measles infection. The antigenic specificity of 66 T cell clones derived from the lines was studied in a blastogenic assay using whole measles virus and two purified virus components, haemagglutinin and nucleocapsid. Thirty-nine of the clones were specific for one of the two...
Topics
- Adult
- Antibodies, Monoclonal
- Antigens, Viral
- Capsid
- Clone Cells
- Epitopes
- HLA Antigens
- Hemagglutinins, Viral
- Humans
- Lymphocyte Activation
- Male
- Measles
