Article
Deriving components of genetic variance for multilocus models.
Genetic epidemiology - 1 Jan 1997
Tiwari H K, Elston R C
Abstract excerpt
Several authors have considered two-locus models as a basis for the inheritance of complex diseases. The purpose of this paper is to give a simple general formulation to derive the additive, dominant, and epistatic effects, and hence the corresponding variance components, for any multilocus model...
Topics
- Alleles
- Chromosome Mapping
- Epistasis, Genetic
- Female
- Gene Frequency
- Genetic Diseases, Inborn
- Genetic Linkage
- Genetic Variation
- Humans
- Male
- Matched-Pair Analysis
- Models, Genetic
- Nuclear Family