Article
The effect of HLA-DRB1 disease susceptibility markers on the expression of RA.
Scandinavian journal of rheumatology - 1 Jan 1997
Rowley M J, Stockman A, Brand C A, Tait B D, Rowley G L, Sherritt M A, Mackay I R, Muirden K D, Bernard C C
Abstract excerpt
The study was designed to examine the effect on clinical expression of rheumatoid arthritis (RA) of HLA alleles, particularly DR4 and DR1 that contain susceptibility sequences for RA in the third hypervariable region (HVR3) of HLA-DRB1. We studied 114 consecutive Australian patients with RA attending a hospital outpatient clinic. The effects on indices of disease severity and activity of HLA DR4 and DR1, the...
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