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Article

Influence of the HLA-DRB1 locus on susceptibility and severity in rheumatoid arthritis.

QJM : monthly journal of the Association of Physicians - 1 Nov 1996

Hall F C, Weeks D E, Camilleri J P, Williams L A, Amos N, Darke C, Gibson K, Pile K, Wordsworth B P, Jessop J D

Abstract excerpt

We examined HLA-DR genotype risk in 288 patients with rheumatoid arthritis who were carefully categorized for disease severity. Five hundred ethnically-matched bone-marrow donors were controls. A hierarchy of positive allelic associations was noted with DRB1*0401 (p < 10(-38), *0404,8 (p < 10(-43), *0405 (p < 10(-8), *10 (p < 10(-3) and *0101,2 (p < 10(-2), while DRB1*0403 was negatively associated (p = 0.02)....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8977961
DOI: 10.1093/qjmed/89.11.821

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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