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Article

Genetic and biochemical characterization of the yeast spo12 protein.

Molecular biology of the cell - 1 Nov 1999

Grether M E, Herskowitz I

Abstract excerpt

We have performed a genetic and biochemical analysis of the SPO12 gene, which regulates meiotic nuclear divisions in budding yeast. When sporulated, spo12 mutants undergo a single meiotic nuclear division most closely resembling meiosis II. We observed that Spo12 protein is localized to the nucleus during both meiotic divisions and that Clb1-Cdc28, Clb3-Cdc28, Clb4-Cdc28, and Clb5-Cdc28 kinase activities during...

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Identifiers

PMID: 10564265
DOI: 10.1091/mbc.10.11.3689
PMCID: PMC25663

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