Article
[p53 as a molecular target for cancer therapy].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Dec 1997
Ishioka C, Osada M, Gamo M, Kanamaru R
Abstract excerpt
Development of novel strategies is required for cancer treatment because most human tumors are refractory to current conventional therapy. During the past decade, a number of oncogenes and tumor suppressor genes have been cloned and the molecular mechanisms as to how mutations in such genes contribute to tumor development are going to be clarified. It is, therefore, a great challenge to develop novel strategies...
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