Article
Enrichment and characterization of dendritic cells from rat renal mesangium.
Scandinavian journal of immunology - 1 Dec 1997
Gieseler R, Hoffmann P R, Kuhn R, Fayyazi A, Stojanovic T, Schlemminger R, Peters J H
Abstract excerpt
Dendritic cells (DC) initiate primary immune reactions and are distributed throughout most tissues. The most potent DC population of the kidney has long been suggested to reside within the glomerular mesangium. Using LEW.1A rats, we enriched and characterized such low-density cells. Mesangial DC generally exhibited round to oval cell bodies and cytoplasmic veils. Phenotypically, these cells were 100% OX-6++, 45%...
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