Timing and effects of template number for gene conversion of major histocompatibility complex genes in the mouse.

Abstract excerpt

Pachytene spermatocytes and haploid spermatocytes from adult mice, as well as testis cells from prepubescent mice were analysed for the presence of gene conversion products resulting from the transfer between the MHC class II genes Ebd and Abk in a PCR assay. Gene conversion products were detected in testis cells as early as in 8 days old mice, where the only existing spermatogenic cells are spermatogonia. The...

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