Article
Alleles of the NRAMP1 gene are risk factors for pediatric tuberculosis disease.
Proceedings of the National Academy of Sciences of the United States of America - 23 Aug 2005
Malik Suneil, Abel Laurent, Tooker Heather, Poon Audrey, Simkin Leah, Girard Manon, Adams Gerald J, Starke Jeffrey R, Smith Kimberly C, Graviss Edward A, Musser James M, Schurr Erwin
Abstract excerpt
Relatively little is known about the human genetics of susceptibility to common diseases caused by bacterial pathogens. Tuberculosis, caused by Mycobacterium tuberculosis, is a major cause of morbidity and mortality worldwide. So far, genetic studies of tuberculosis susceptibility have largely been focused on adult patients despite the fact that tuberculosis is highly prevalent among children. To study the host...
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