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Article

CDKN2A (p16INK4A) somatic and germline mutations.

Human mutation - 1 Jan 1996

Smith-Sørensen B, Hovig E

Abstract excerpt

The cell cycle is composed of a series of steps that can be negatively or positively regulated by various factors. A group of low-molecular-weight proteins have recently been identified that specifically inhibit the function of cyclin-dependent kinases in mammalian cells. Inactivation of the CDKN2A gene (also known as p16INK4A and MTS1) attracted considerable interest after it was mapped to 9p21, a locus for...

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Identifiers

PMID: 8723678
DOI: 10.1002/(SICI)1098-1004(1996)7:4<294::AID-HUMU2>3.0.CO;2-9

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Source receipt: pubmed, retrieved 7 Sept 2026.

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