CDKN2A (p16INK4A) somatic and germline mutations.

doi:10.1002/(SICI)1098-1004(1996)7:4<294::AID-HUMU2>3.0.CO;2-9

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Article

CDKN2A (p16INK4A) somatic and germline mutations.

Human mutation - 1 Jan 1996

Smith-Sørensen B, Hovig E

Abstract excerpt

The cell cycle is composed of a series of steps that can be negatively or positively regulated by various factors. A group of low-molecular-weight proteins have recently been identified that specifically inhibit the function of cyclin-dependent kinases in mammalian cells. Inactivation of the CDKN...

Topics

Carrier Proteins
Cyclin-Dependent Kinase Inhibitor p16
Germ-Line Mutation
Humans
Mutation
Neoplasms

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