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Article

Cyclin-dependent kinase inhibitors (CKIs) and hematological malignancies.

Hematology and cell therapy - 1 Aug 1996

Baghdassarian N, Ffrench M

Abstract excerpt

Cell proliferation control is ensured by a group of proteins named cyclin-dependent kinases (CDKs), the activation of which is dependent on phosphorylation and cyclin association. In parallel, these CDKs are negatively controlled by two distinct groups of inhibitory proteins, the cyclin-dependent kinase inhibitors (CKIs). The first group, including p16Ink4a, p15Ink4b, p18Ink4c and p19Ink4d, is specific for the G1...

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Source

Identifiers

PMID: 8891723
DOI: 10.1007/s00282-996-0313-4

Genes

CDK6
CDK4
PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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