Cyclin-dependent kinase inhibitors (CKIs) and hematological malignancies.

doi:10.1007/s00282-996-0313-4

Back to search

Article

Cyclin-dependent kinase inhibitors (CKIs) and hematological malignancies.

Hematology and cell therapy - 1 Aug 1996

Baghdassarian N, Ffrench M

Abstract excerpt

Cell proliferation control is ensured by a group of proteins named cyclin-dependent kinases (CDKs), the activation of which is dependent on phosphorylation and cyclin association. In parallel, these CDKs are negatively controlled by two distinct groups of inhibitory proteins, the cyclin-dependent...

Topics

Cyclin-Dependent Kinases
Enzyme Inhibitors
Hematologic Diseases
Humans
Mutation
Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.