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Article

Yeast cycloheximide-resistant crl mutants are proteasome mutants defective in protein degradation.

Molecular biology of the cell - 1 Dec 1997

Gerlinger U M, Gückel R, Hoffmann M, Wolf D H, Hilt W

Abstract excerpt

In 1988 McCusker and Haber generated a series of mutants which are resistant to the minimum inhibitory concentration of the protein synthesis inhibitor cycloheximide. These cycloheximide-resistant, temperature-sensitive (crl) mutants, in addition, exhibited other pleiotropic phenotypes, e.g., incorrect response to starvation, hypersensitivity against amino acid analogues, and other protein synthesis inhibitors....

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Identifiers

PMID: 9398670
DOI: 10.1091/mbc.8.12.2487
PMCID: PMC25722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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