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Article

Structural Analysis of the Human BIN1 Gene

1 Dec 1997

Abstract excerpt

BIN1 is a putative tumor suppressor that was identified through its interaction with the MYC oncoprotein. To begin to identify elements of BIN1 whose alteration may contribute to malignancy, we cloned and characterized the human BIN1 gene and promoter. Nineteen exons were identified in a region of >54 kilobases, six of which were alternately spliced in a cell type-specific manner. One alternately spliced exon...

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PMID: 9395479
DOI: 10.1074/jbc.272.50.31453

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