Article
Pathogenicity and protective effect of rough mutants of Salmonella species in germ-free piglets.
Infection and immunity - 1 Dec 1997
Dlabac V, Trebichavský I, Reháková Z, Hofmanová B, Splíchal I, Cukrowska B
Abstract excerpt
In this study, two stable, rough, streptomycin-sensitive Salmonella mutants with different types of genetic defects were used to colonize groups of germ-free (GF) piglets. The lipopolysaccharide (LPS) of Salmonella typhimurium SF 1591 was of the Ra chemotype (complete core), whereas the LPS of the S. minnesota mR 595 deep-rough mutant contained only lipid A and 2-keto-3-deoxyoctulosonic acid (Re chemotype). Both...
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