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Article

Design of hydrophobic core of E. coli malate dehydrogenase based on the side-chain packing.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 1997

Kono H, Nishiyama M, Tanokura M, Doi J

Abstract excerpt

We have developed computational programs for the de novo design of hydrophobic cores of proteins. The first program optimizes side-chain conformations using an updated rotamer library for potential hydrophobic residues, based on the backbone structure of the protein of interest. The second progra...

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PMID: 9390293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9390293-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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