Article
Extraction of hidden Markov model representations of signal patterns in DNA sequences.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 1996
Yada T, Ishikawa M, Tanaka H, Asai K
Abstract excerpt
We have developed a method to extract the signal patterns in DNA sequences. In this method, the Genetic Algorithm (GA) and Baum-Welch algorithm are used to obtain the best Hidden Markov Model (HMM) representations of the signal patterns in DNA sequences. The GA is used to search the best network shapes and the initial parameters of the HMMs. Baum-Welch algorithm is used to optimize the HMM parameters for the...
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