Article
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources.
BMC bioinformatics - 9 Feb 2006
Stanke Mario, Schöffmann Oliver, Morgenstern Burkhard, Waack Stephan
Abstract excerpt
BACKGROUND: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons and EST and protein alignments. However, such evidence is often incomplete and usually uncertain. The extrinsic evidence is usually not sufficient to recover the complete gene structure of all genes completely and the available evidence is...
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