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Article

Mutants of basic fibroblast growth factor identify different cellular response programs.

Growth factors (Chur, Switzerland) - 1 Jan 1997

Leenders W P, van Hinsbergh V W, van Genesen S T, Schoenmakers J G, van Zoelen E J, Lubsen N H

Abstract excerpt

Mutations, expected to affect the intracellular routing, i.e. additional nuclear localization sequences (NLS; the natural 23 kDa isoform and a 17D27R mutant) and/or a deletion of amino acids 26-29 (23 delta 26-29 and 17 delta 26-29), were introduced in basic fibroblast growth factor (bFGF). The mutants were assayed for their mitotic activity and their capacity to induce a tissue-specific response in human...

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PMID: 9386987
DOI: 10.3109/08977199709021521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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