Article
Subunit interaction in extracellular superoxide dismutase: effects of mutations in the N-terminal domain.
Protein science : a publication of the Protein Society - 1 Nov 1997
Stenlund P, Andersson D, Tibell L A
Abstract excerpt
Human extracellular superoxide dismutase (hEC-SOD) is a secreted tetrameric protein involved in protection against oxygen free radicals. Because EC-SOD is too large a protein for structural determination by multidimensional NMR, and attempts to crystallize the protein for X-ray structural determination have failed, the three-dimensional structure of hEC-SOD is unknown. This means that alternative strategies for...
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